Efficacy of Diclofenac Sodium in Pain Relief after Conventional Radiofrequency Denervation for Chronic Facet Joint Pain: A Double‐Blind Randomized Controlled Trial

Efficacy of Diclofenac Sodium in Pain Relief after Conventional Radiofrequency Denervation for Chronic Facet Joint Pain: A Double?Blind Randomized Controlled Trial - Ma - 2010 - Pain Medicine - Wiley Online LibrarySkip to Main Content

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PUBLICATIONSBROWSE BY SUBJECTRESOURCESABOUT US LOGIN Enter e-mail address Enter password REMEMBER ME NOT REGISTERED ?FORGOTTEN PASSWORD ?INSTITUTIONAL LOGIN > JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy JOURNAL MENU Journal Home FIND ISSUES Current IssueAll IssuesVirtual Issues FIND ARTICLES Early View GET ACCESS Subscribe / Renew FOR CONTRIBUTORS Author GuidelinesSubmit an Article ABOUT THIS JOURNAL Society InformationNewsOverviewEditorial BoardPermissionsAdvertiseContact SPECIAL FEATURES Professional OpportunitiesPainPoints Blog Efficacy of Diclofenac Sodium in Pain Relief after Conventional Radiofrequency Denervation for Chronic Facet Joint Pain: A Double?Blind Randomized Controlled TrialKe Ma PhD1, Mi Yiqun MS2, Tao Wu MS1, Wenhao Wang MS1, Xiaoming Liu PhD1, Xiaohui Huang PhD3, Yingwei Wang PhD1,*Article first published online: 28 OCT 2010

DOI: 10.1111/j.1526-4637.2010.00978.x

Wiley Periodicals, Inc.

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How to CiteMa, K., Yiqun, M., Wu, T., Wang, W., Liu, X., Huang, X. and Wang, Y. , Efficacy of Diclofenac Sodium in Pain Relief after Conventional Radiofrequency Denervation for Chronic Facet Joint Pain: A Double?Blind Randomized Controlled Trial. Pain Medicine, no. doi: 10.1111/j.1526-4637.2010.00978.x

Author Information1

Department of Anesthesiology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai

2

Department of Acupuncture Massage and Traumatology, The Shanghai Sixth People's Hospital, Shanghai JiaoTong University, Shanghai

3

College of Pharmacy, Anhui Medical University, Hefei, China

*Correspondence: Yingwei Wang PhD,

*Correspondence: Yingwei Wang, PhD, Department of Anesthesiology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China. Tel: 86?21?65790000 ext 7951; Fax: 86?21?65153984; E?mail: wangyingwei@yahoo.com.

Publication HistoryArticle first published online: 28 OCT 2010 SEARCH Search Scope All contentPublication titlesIn this journalIn this issue Search String Advanced >Saved Searches > SEARCH BY CITATION Volume: Issue: Page: ARTICLE TOOLSGet PDF (456K)Save to My ProfileE-mail Link to this ArticleExport Citation for this ArticleRequest Permissions AbstractArticleReferencesCited By View Full Article (HTML) Get PDF (456K) Keywords:Low Facet Pain;Radiofrequency;Diclofenac Sodium;Visual Analgesia Score;Oswestry Disability IndexAbstract

Objectives.? Many patients experience pain for a short duration after conventional radiofrequency (CRF) denervation for lumbar facet pain. The aim of the present study was to evaluate the efficacy and cost of administering diclofenac sodium for the relief of pain after CRF denervation.

Methods.? After denervation, 66 patients were randomly allocated into three groups to receive either placebo for 7 days (group A), diclofenac sodium for 3 days (group B), or diclofenac sodium for 7 days (Group C). The patients' pain visual analgesia score (VAS) and side effect were recorded at baseline 1, 7, 14, 30, and 60 days after treatment. Oswestry Disability Index (ODI), Patients' Satisfaction Score (PSS), and dosage and cost of the drugs used for pain management were recorded at baseline, 30 and 60 days after treatment.

Results.? VAS in groups B and C both was less than that in group A at 1 and 7 days after treatment (P???>?0.05). The cost of analgesic administration in group B was significantly less than in groups A and C (P?

Conclusion.? Diclofenac sodium administration improves analgesia and the PSS after CRF denervation. Compared to a 7?day dosage, a 3?day diclofenac sodium therapy has similar efficacy and less cost for the treatment of pain after CRF neurotomy. [ISRCTN68542008].

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